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http://cibnor.repositorioinstitucional.mx/jspui/handle/1001/952| Phenotypic, chemical and functional characterization of cyclic nucleotide phosphodiesterase 4 (PDE4) as a potential anthelmintic drug target | |
| Thavy Long Liliana Carolina Rojo Arreola | |
| Acceso Abierto | |
| Atribución-NoComercial-SinDerivadas | |
| doi.org/10.1371/journal.pntd.0005680 URL: http://journals.plos.org/plosntds/ | |
| flatworm disease, tropical disease | |
| "Reliance on just one drug to treat the prevalent tropical disease, schistosomiasis, spurs the search for new drugs and drug targets. Inhibitors of human cyclic nucleotide phosphodiesterases (huPDEs), including PDE4, are under development as novel drugs to treat a range of chronic indications including asthma, chronic obstructive pulmonary disease and Alzheimer's disease. One class of huPDE4 inhibitors that has yielded marketed drugs is the benzoxaboroles (Anacor Pharmaceuticals)." | |
| McGill University | |
| 2017 | |
| Artículo | |
| PLOS Neglected Tropical Diseases | |
| Inglés | |
| PARASITOLOGÍA | |
| Versión publicada | |
| publishedVersion - Versión publicada | |
| Aparece en las colecciones: | Artículos |
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| Fichero | Tamaño | Formato | |
|---|---|---|---|
| PLOS Neglected Tropical Diseases 11 7 e0005680.pdf | 11.77 kB | Adobe PDF | Visualizar/Abrir |